The impact and effectiveness of pneumococcal vaccination in Scotland for those aged 65 and over during winter 2003/2004.

BMC Infect Dis · 2008 · PMC2386805 · PMID 18433473

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highly significantno p-value reported

Reductions in the winter season incidence rate of IPD were highly significant for all those aged 75+: males SIR = 58.8 (95%CI: 41.6, 80.8); females SIR = 70.0 (95%CI: 55.1, 87.8).

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did not reach statistical significanceno p-value reported

The very low numbers of non-vaccine component strains in IPD patients (five out of the six cases being in 65+ patients, three of whom were vaccinated) means that the VE estimate by the indirect cohort method was associated with a high range of uncertainty and did not reach statistical significance (VE (65+) = 51% (95% CI:-278, 94).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.