Barely Significant
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Surrogate markers in antiangiogenesis clinical trials.

Br J Cancer · 2003 · PMC2394225 · PMID 12838293

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In addition, LSC-mediated analysis of additional surrogate markers hypothesised to be effected by endostatin including nuclear hypoxia-inducible factor-1 α and endothelial cell Bcl-2 levels peaked at similar doses of endostatin but failed to reach statistical significance.

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