highly significantP <0.0001
We found statistically highly significant difference between the three prognostic groups for both DFS and DSS ( P <0.0001, Figure 2 ).
We found statistically highly significant difference between the three prognostic groups for both DFS and DSS ( P <0.0001, Figure 2 ).
In the latter case, cystatin C turned out to be of marginal significance ( P =0.067, HR=0.25, 95% CI 0.07–0.90).
Among nonlaryngeal tumour samples, no difference was found in matched pairs of normal mucosa and its tumour counterparts, and marginally significant trend of higher cystatin C concentrations was observed in early disease compared to advanced tumours (UICC pTNM stages I–II vs III–IV: 18.1 vs 13.8 ng mgp −1 , P =0.052).