A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer.

Patients with one or two −6BP alleles of the TS-3′UTR genotype appeared to have a higher risk of progressing comparing to the +6BP/+6BP homozygotes, although this association did not reach statistical significance in the univariate analysis ( P =0.22) ( Table 4 ).

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