nearly significantP =0.02
Similarly, the differences in the changes of LDL/HDL ratios and total cholesterol/HDL ratios were insignificant between patients with amenorrhoea and irregular menstruation ( P =0.50 and 0.84), but the differences in the changes of LDL/HDL ratios were significant ( P =0.006) and of total cholesterol/HDL ratios nearly significant ( P =0.02) between patients with regular menses and irregular or absent menstruation (amenorrhoea).