Even though there tended to be a greater number of macrophages in Dstn corn1/corn1 Il8rb −/− cornea as compared to Dstn corn1/corn1 Il8rb +/− cornea, this difference did not reach statistical significance (101.9±29.13 versus 68.75±10.48, p = 0.345) ( Fig 4A,B ).
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Defects in actin dynamics lead to an autoinflammatory condition through the upregulation of CXCL5.
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