Compared to placebo, long-term antibiotics resolve otitis media with effusion (OME) and prevent acute otitis media with perforation (AOMwiP) in a high-risk population: a randomized controlled trial.

BMC Pediatr · 2008 · PMC2443129 · PMID 18513453

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did not reach statistical significanceno p-value reported

Beta-lactamase producing NCHi were detected more often in amoxicillin (10%) than placebo (5%) swabs; these latter differences did not reach statistical significance.

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