Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial.

Crit Care · 2008 · PMC2447606 · PMID 18423009

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did not reach statistical significanceno p-value reported

Melatonin therapy was associated with a 1-hour increase in nocturnal sleep compared with placebo, corresponding to an increase of 47%, although the SEI difference did not reach statistical significance.

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