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Reduced meiotic recombination on the XY bivalent is correlated with an increased incidence of sex chromosome aneuploidy in men with non-obstructive azoospermia.

Mol Hum Reprod · 2008 · PMC2453242 · PMID 18583429

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The frequency of XY disomy was 2-fold higher than in controls, but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.