Barely Significant
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Chronic heart failure in Japan: implications of the CHART studies.

Vasc Health Risk Manag · 2008 · PMC2464764 · PMID 18629369

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a clear trendno p-value reported
There is a clear trend for the increase in death due to heart disease since 1950s (there was a temporary sharp decline in 1995 due to the tenth revision of the International Classification of Diseases regarding the description of diagnosis in death certificates).

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