Quantitative methylation analyses of resection margins predict local recurrences and disease-specific deaths in patients with head and neck squamous cell carcinomas.

Although this disparity in tumour sites did not reach statistical significance ( P =0.067, Fisher's exact test), probably due to the small sample size, we were nonetheless reassured that the specificity of the molecularly negative margins could not be attributed to the selection of tumour sites with favourable prognosis.

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