CRPV genomes with synonymous codon optimizations in the CRPV E7 gene show phenotypic differences in growth and altered immunity upon E7 vaccination.

PLoS One · 2008 · PMC2491898 · PMID 18698362

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moderately significantp<0.03actually significant

There was a highly significant difference between the growth rates of E7/18 and E7/22 genomes (p<0.001, unpaired student t test) and a moderately significant difference between E7/18 and wild type at later time points (p<0.03, unpaired student t test; Fig 8 ).

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