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Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice.

Diabetes · 2008 · PMC2494682 · PMID 18477810

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A similar trend was also observed in the splenic T-cells examined but did not reach statistical significance (17.69 ± 2.11 vs. 15.02 ± 1.69%).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.