Percutaneous coronary intervention in patients with acute coronary syndrome: focus on bivalirudin.

Although there was no significant difference in mortality at 12 month follow-up, there were patient subgroups that seemed to have a strong trend towards a reduction in mortality: elderly over 75 years of age, diabetics, renal insufficiency (as defined as a creatinine clearance less than 60 mL/min), unstable angina, or any previous heparin therapy ( Lincoff et al 2003 ).

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