Multiple advantageous amino acid variants in the NAT2 gene in human populations.

A similar excess of intermediate frequency variants was observed in non-African populations, which tend to have positive Tajima's D values at the genome-wide level; yet, the Tajima's D value at NAT2 is unusual in the European and Asian samples (though only marginally significant in the latter) when compared to neutral expectations for two different bottleneck models.

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