HIV-1 with multiple CCR5/CXCR4 chimeric receptor use is predictive of immunological failure in infected children.

PLoS One · 2008 · PMC2538568 · PMID 18820725

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0740

boldest claim

The sentences

a trend towards significancep = 0.056so close (0.05 < p ≤ 0.1)

2 out of 6, respectively) with a trend towards significance (p = 0.056, Perason's chi-square test).

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did not reach statistical significancep = 0.074so close (0.05 < p ≤ 0.1)

Transmitting mothers carried more often viruses able to use both CCR5 and CXCR4 as coreceptors than non transmitting mothers, 29% (7 out of 24) and 8% (3 out of 35), respectively, but this difference did not reach statistical significance (p = 0.074, Fisher's Exact Test) ( Figure 2 ).

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