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Specific requirements for automation of immunoassays in 1990.

J Automat Chem · 1991 · PMC2547906 · PMID 18925297

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This reaction can be directly detected by turbidity measure- ments, or indirectly detected by including a 'tracer'. Tracers have been radioisotopes for nearly three decades. There is now a clear trend to replace these tracers by non- isotopes for two principal reasons: to avoid radioactivity, and to improve the chances of automation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.