G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes.

Nominally significant association across the three populations ( P < 0.05) was observed for 33 SNPs of 344, with P values ranging from P = 1.79 × 10 −5 to P = 0.050 (supplementary Table 3).

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