A Poisson mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology.

This figure demonstrates a clear trend that with the increase of the number of Pol II binding quantity in the gene transcript region, a less relative change is required for a gene to be considered as major change (red dots, Z i ≥ 0.9), or minor change (green dots, 0.1 ≤ Z i < 0.9), where Z i is a posterior probability that the Pol II binding quantity changed after E2 treatment.

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