Barely Significant
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Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance.

BMC Med Genomics · 2008 · PMC2561034 · PMID 18823550

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However, the absolute change was somewhat reduced, and for most genes tested the changes were at best trending towards significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.