Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy.

Br J Cancer · 2008 · PMC2567080 · PMID 18797464

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significanceP =0.08so close (0.05 < p ≤ 0.1)

Grade 2 and 3 cumulative peripheral neuropathy was more common in patients with the Ile/Ile genotype (29/44 patients, 66%) than in patients with Ile/Val or Val/Val genotype (42/82 patients, 51%), but the difference did not reach statistical significance ( P =0.08).

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