Valvular regurgitation and surgery associated with fenfluramine use: an analysis of 5743 individuals.

BMC Med · 2008 · PMC2585088 · PMID 18990200

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0900

boldest claim

The sentences

highly significantp < 0.0001actually significant

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

The association of duration of use remained highly significant for moderate or greater AR ( p < 0.0001) but the association with moderate or greater MR did not reach statistical significance ( p = 0.09, one-sided) while the trend for moderate or greater TR remained statistically significant ( p = 0.007, one-sided).

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of borderline significancep = 0.09so close (0.05 < p ≤ 0.1)

Age was also strongly associated with presence of pulmonary hypertension ( p < 0.0001, OR 1.039 per year of increasing age, 95% CI 1.025–1.054) while gender was of borderline significance ( p = 0.09, OR 1.6 for female gender, 95% CI 0.92–2.9), as was body mass index (BMI) (OR 1.004 per BMI unit increase, 95% CI 1.000–1.008, p = 0.08).

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