Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice.

While HDM exposure had little impact on absolute pDC number at 24 hours after allergen exposure, it tended to increase the number of pDCs present in the lung after 72 hours, although this did not reach statistical significance ( Figure 4e ).

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