An A2A adenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models.

Although differences between untreated and treated mice were observed, these did not reach statistical significance for the following cytokines/chemokines: IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-12 p40, IL-12 p70, KC, and RANTES (data not shown).

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