showed a trendp = .08
Although the controls were four times more likely to overexpress HER-2/neu, the difference was not statistically significant (Fisher's exact, 2 tail, p = .22). A chi-square analysis of the percentage of cells in S-phase showed a trend toward a dif- ference between cases and controls (mantel-haenszel chi-square, p = .08), but it was not statistically significant.