High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability.

Br J Cancer · 2008 · PMC2600708 · PMID 18985040

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showed a trendP =0.06so close (0.05 < p ≤ 0.1)

High-level microsatellite instability CRCs showed a trend towards a higher infiltration with FOXP3-positive cells in the tumour stroma (median: 181.5 cells per 0.25 mm 2 in MSI-H vs 137.1 cells per 0.25 mm 2 in MSS, P =0.06) and a significantly higher intraepithelial infiltration with FOXP3-positive Treg cells (median: 8.5 cells per 0.25 mm 2 in MSI-H vs 3.1 cells per 0.25 mm 2 in MSS, P <0.001).

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