Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02.

PLoS One · 2008 · PMC2602972 · PMID 19093004

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a positive trendno p-value reported

A positive trend between antigen dose, antibody response and in vitro parasite growth inhibition could be detected, although the effect of antigen dose on immunogenicity was negligible compared to the effect of varying the adjuvant.

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showed a trendno p-value reported

Vaccinees receiving 50 μg PfAMA1 generally showed a trend towards higher antibody titers than the corresponding 10 μg group, except for the AS02 groups where antibody titers were not antigen dose-dependent.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.