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Granulocyte stimulating factor attenuates hypoxic-ischemic brain injury by inhibiting apoptosis in neonatal rats.

Yonsei Med J · 2008 · PMC2615357 · PMID 18972605

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In HG, the increased percentage of apoptotic cells in Q4 (annexin V+/PI-) and decreased percentage of live cells in Q3 (annexin V-/PI-) observed in HC were significantly improved but the attenuation of secondary necrotic cells in Q2 (annexin V+/PI+) did not reach statistical significance, and the damaged cells in Q1 (annexin V-/PI+) were not significantly different from those in HC ( Table 1 ).

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