Ryanodine (100 μmol/l), alone or in combination with xestospongin C (1 μmol/l), also suppressed thapsigargin-induced propidium iodide incorporation, although this trend did not reach statistical significance ( Fig. 4 B ).
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Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.
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