Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic patients.

Indeed, among intensively treated patients, the risk of developing diabetic retinopathy was 3.2 times higher in those with immeasurable fasting plasma C-peptide than in those with higher residual pancreatic secretion, whereas data from conventionally treated patients did not reach statistical significance ( 4 ).

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