Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.

14-gene signature in study with tamoxifen treated patients In the study of 45 tamoxifen-treated patients (see Additional file 9 for clinical and pathological characteristics of the patients), each unit increase in the MS resulted in an estimated 4.9 percent increase in the hazard for DMFS although this association did not reach statistical significance (p = 0.085).

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