For HIV-2 ROD-A , a trend towards higher viral gene expression was observed for macrophages from hCycT1-tg rats compared to n-tg rats, but this difference did not reach statistical significance (Fig. 5C , right panel).
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Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo.
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