Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

Of note we observed a borderline significant positive association with the common Pro241Pro variant in CCND1 among current users of HRT (OR = 1.21; 95% CI, 1.00–1.46), however no significant interactions were observed by postmenopausal hormone use status (see Additional file 1 , Supplementary table 6).

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We observed nominally significant positive associations with two coding variants in ethnic-pooled analyses ( NCOR2 : His52Arg, OR = 1.79; 95% CI, 1.05–3.05; CALCOCO1 : Arg12His, OR = 2.29; 95% CI, 1.00–5.26).

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