Do implementation issues influence the effectiveness of medications? The case of nicotine replacement therapy and bupropion in UK Stop Smoking Services.

Forty four percent (54/123) of clients reporting using at least 14 bupropion tablets (range 14–30) in the week prior to their quit date (the minimum recommended) were abstinent at 3–4 weeks compared with 32% (12/38) of those using below this amount (range 1–13); however this difference did not reach statistical significance (p = .26).

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