Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain.

Mol Pain · 2008 · PMC2644687 · PMID 19094200

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did not reach statistical significanceno p-value reported

In the present study the serum concentrations of morphine, morphine-6-glucuoride (M6G) and morphine-3-glucuronide (M3G) reflected the different morphine doses between haplotypes (Table 4b ), but did not reach statistical significance as seen for the morphine dose.

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