Exploiting proteomic data for genome annotation and gene model validation in Aspergillus niger.

In all but one case, a homologous gene is predicted in the DSM annotation and a UniProt homologue is detected with a highly significant e-value of 10 -30 or better in another species.

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Overall, these results are generally reassuring since the proteins used here represent a range of predicted gene models and there is a clear trend in decreasing protein mass down the gel.

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