The frequencies of the potential minor risk alleles of rs502933, rs477181, and rs4450508 were higher among overweight/obese and obese subjects than among lean subjects; however, these differences did not reach statistical significance ( Table 2 ; data not shown).
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Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.
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The sentences
This association was only borderline significant in the Danish population; however, this was probably due to a limited sample size ( n morbid-obese = 283), and the less pronounced effect in the Danish population is likely due to a lower mean BMI in the Danish morbidly obese case individuals.