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The intraportal injection model: a practical animal model for hepatic metastases and tumor cell dissemination in human colon cancer.

BMC Cancer · 2009 · PMC2648996 · PMID 19166621

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The fact that the differences in the rate of MRD following intraportal injection of different numbers of tumor cells did not reach statistical significance is due to the small number of animals investigated.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.