Gag mutations strongly contribute to HIV-1 resistance to protease inhibitors in highly drug-experienced patients besides compensating for fitness loss.

PLoS Pathog · 2009 · PMC2652074 · PMID 19300491

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did not reach statistical significanceno p-value reported

In virus VIS20, the same phenomenon was observed, albeit on a smaller scale, and the difference in RC between AS and BS clones did not reach statistical significance.

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