Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche.

PLoS Genet · 2009 · PMC2652107 · PMID 19282985

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hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

marginally significantp <0.10so close (0.05 < p ≤ 0.1)

Several imputed SNPs, i.e., rs4987053 in exon 3, rs17217831 in intron 2, rs13067058 in promoter region, and rs3091309 in intron 1, achieved significant ( p <0.05) or marginally significant ( p <0.10) p values in our GWAS sample.

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nominally significantno p-value reported

We found that three SNPs in or near the CCR3 gene achieved nominally significant p values; a SNP rs13084656 , located in the promoter region, achieved a p value of 0.039; another SNP rs2157056 , located downstream of the gene, achieved a p value of 6.27×10 −3 ; a third SNP rs2373156 , located in the intronic region, achieved a p value of 0.050.

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