A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.

PLoS Genet · 2009 · PMC2652833 · PMID 19300499

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moderately significantno p-value reported

Follow-Up of Moderately Significant SNPs To possibly identify SNPs with genuine but weak associations to warfarin dose, we excluded VKORC1 , CYP2C9 , CYP4F2 and identified 40 other GWAS loci for follow-up genotyping exhibiting multivariate regression p-values below 0.0002, and selected 40 SNPs representing these loci for genotyping.

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