A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.

BMC Cardiovasc Disord · 2009 · PMC2653470 · PMID 19222850

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did not reach statistical significanceno p-value reported

Although there was an important difference in the percentage of reduction (24% reduction in severity score measured by digital image analysis) in atherosclerosis from control compared with the treatment group, these differences did not reach statistical significance.

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a decreasing trendno p-value reported

However, the morphological analyses of the atherosclerotic lesion showed just a decreasing trend compared to the experimental group.

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