FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation.

PLoS One · 2009 · PMC2654098 · PMID 19287496

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Digital densitometry of these immunostained sections showed a trend of progressive increase in FOXM1 protein levels from moderate dysplasia to lymph node metastasis ( Fig. 1J ).

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