As shown in Fig 6a,b , we detected slightly fewer Ki67-positive keratinocytes in G3 Terc −/− p53 +/+ untreated interfollicular (IFE) skin compared to G3 Terc −/− p53 −/− or wild type skin, although the differences did not reach statistical significance.
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A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres.
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