Glycation of paraoxonase-1 inhibits its activity and impairs the ability of high-density lipoprotein to metabolize membrane lipid hydroperoxides.

Diabet Med · 2008 · PMC2659363 · PMID 18937674

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

did not reach statistical significanceP = 0.058so close (0.05 < p ≤ 0.1)

Although there were correlations between PON1 activity and HDL hydroperoxide metabolism, these did not reach statistical significance in the Type 2 diabetes ( r = −0.624, P = 0.058) or CHD ( r = −0.598, P = 0.06) groups.

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