Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis.

J Inflamm (Lond) · 2009 · PMC2673212 · PMID 19368720

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0650

boldest claim

The sentences

highly significantp < 0.001actually significant

Proliferation following stimulation with either LPS or Con A was reduced to a highly significant extent (p < 0.001) in mice treated with either 1 mg/week or 5 mg/week of anti-IL-6 antibody compared to control.

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approached significancep = 0.065so close (0.05 < p ≤ 0.1)

Mice receiving 1 mg/week exhibited a significant reduction in staining loss using aldehyde fuchsia (p < 0.025) and approached significance for a reduction in staining loss using Toluidine Blue (p = 0.065).

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