Maternal circulating levels of activin A, inhibin A, sFlt-1 and endoglin at parturition in normal pregnancy and pre-eclampsia.

In normal pregnancy, during labour, ( Fig 3A ) there was no significant change in sFlt-1 levels at full dilatation, although an increasing trend was noted it probably did not achieve statistical significance due to small sample size SFlt-1 levels significantly decreased after 24 hours (82% p<0.007) of delivery.

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During labour, there was no increase in plasma levels in normal pregnant women but in pre-eclampsia women, inhibin A levels at full dilatation (1240 (39–12669) pg/ml) were higher compared to pre-delivery values (944.7 (272–5274) pg/ml), although this increase did not reach statistical significance.

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