The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients.

Br J Cancer · 2009 · PMC2676551 · PMID 19367284

Europe PMC DOI

hedged sentence

0.3300

closest p · 6.6× alpha

0.3300

boldest claim

The sentences

did not reach statistical significanceP =0.33not close (p > 0.1)

However, the association of methylation in serum DNA of ESR1 with case status did not reach statistical significance: ESR1 was hypermethylated in 20% of breast cancer patients and 10.5% of healthy controls ( P =0.33).

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