Our recent study showed a trend of increase in MMP-1 expression in periodontal tissues across patients with neither diabetes nor periodontal disease, patients with periodontal disease alone, and patients with both diseases ( 10 ).
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Interleukin-6 released from fibroblasts is essential for up-regulation of matrix metalloproteinase-1 expression by U937 macrophages in coculture: cross-talking between fibroblasts and U937 macrophages exposed to high glucose.
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