For instance, although Cannon and colleagues reported that mortality associated with longer door-to-balloon time manifested after two or more hours of delay, there is a clear trend towards increased mortality in patients with door-to-balloon times of 61-90 minutes and 91-120 minutes. 13 Furthermore, the few studies that have also modelled time to treatment as a continuous variable have similarly shown increases in adverse outcomes associated with any delay in treatment. 2 3 As such, differences in study findings concerning the specific shape of the association of door-to-balloon time and mortality largely reflect the manner in which different studies have modelled time to treatment rather than contradictory findings regarding the relation between time and outcomes.
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Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarction: national cohort study.
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